Product Details

• Paperback: 121 pages
• Publisher: Springer; 1 edition (March 17, 2009)
• Language: English
• ISBN-10: 3642005128
• ISBN-13: 978-3642005121.

Product Description

The discovery of the neuroendocrine features of Leydig cells gave rise to the hypothesis of a potential neuroectodermal and/or neural crest origin of testicular Leydig cells. In an experimental animal model the authors revealed that adult Leydig cells originate by transdifferentiation from stem/progenitor cells (pericytes and smooth muscle cells), underlying the close relationship of Leydig cells with testis microvasculature. This and the supporting data from the literature provided the basis for revealing the pericytes as a common adult stem cell type of mammalian species. Distributed by the microvasculature through the entire body, the pericyte, acting as a resting early pluripotent adult stem cell, provides an ingenious system to assure the maintenance, physiological repair and regeneration of organs, each under the influence of specific local environmental factors.

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• Paperback: 822 pages
• Publisher: Sinauer Associates, Inc.; Third Edition edition (April 11, 2005)
• Language: English
• ISBN-10: 0878935762
• ISBN-13: 978-0878935765

Product Description

Written for upper-level undergraduates and graduate students, this text provides an integrated presentation of the expanding field of behavioural endocrinology – the study of hormone-behaviour interactions. Using a comparative approach, the text explores how hormone-behaviour interactions have evolved in both humans and non-human animals to solve common problems in survival and reproduction. Topics include: the interactions between hormones and sexually dimorphic behaviours; mating and parental behaviours; homeostatic and rhythmic behaviours; as well as learning, memory and mood. The text is written for upper-level undergraduates and graduate students in psychology or biology. Summaries at the end of each chapter outline key points. Discussion questions and suggested reading are also included for each chapter.

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• Paperback: 272 pages
• Publisher: Mosby; 1 edition (February 7, 2008)
• Language: English
• ISBN-10: 0723434085
• ISBN-13: 978-0723434085.

Product Description

This title is directed primarily towards health care professionals outside of the United States. It is written for those doctors starting their career in this specialty (or in general internal medicine). The text presents a succinct account of the subject concentrating on diagnostic techniques, treatment and management. Throughout extensive use is made graphics, lists and tables. The aim is to provide a ‘bridge’ between introductory undergraduate texts and the very large and expensive major reference works. Wherever possible evidence-based treatment options are given and referenced. A detailed list of further reading is also provided.

• Series aimed at specialist registrar level
• Matches published training guidelines
• Succinct style making use of bullet points, boxes, tables, graphics etc
• Highly accessible four-colour design.

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• Hardcover: 944 pages
• Publisher: Saunders; 6 edition (May 27, 2009)
• Language: English
• ISBN-10: 141604907X
• ISBN-13: 978-1416049074.

Product Description

Thoroughly revised and now enhanced with color artwork, the new edition of this premier reference continues to offer the latest information on the diagnosis and management of reproductive endocrine disorders. National and international leaders from the field of reproductive endocrinology-including 30 new authors-equip you with coverage that encompasses the full spectrum of reproductive pathophysiology and disorders, from pregnancy and birth to reproductive aging. Full-color illustrations and new drawings provide a real-life depiction of basic cell structures and endocrine responses for a better understanding of the material, while new chapters explore the issues shaping today’s practice.

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Product Details

• Hardcover: 560 pages
• Publisher: Academic Press; 4 edition (December 11, 2006)
• Language: English
• ISBN-10: 0120887681
• ISBN-13: 978-0120887682.

Product Description

One of the only books to discuss all vertebrates, the fourth edition of Vertebrate Endocrinology has been completely reorganized and updated to explore the intricate mechanisms that control human physiology and behavior as well as that of other vertebrate animals. Perfect for students in endocrinology, zoology, biology and physiology, it allows readers to gain both an understanding of the intricate relationships among all of the body systems and their regulation by hormones and other bioregulators, but also a sense of their development through evolutionary time as well as the roles of hormones at different stages of an animal’s life cycle.

Chapters have been reorganized to more closely follow traditional classroom presentation and extensive suggested readings are included at the end of each chapter allowing the reader to obtain further information as well as connect concepts to the literature on which the book is based. For the first time, this edition features four-color illustrations as well as an ancillary web site with additional materials for instructors.

* Provides a complete overview of the endocrine system of vertebrates by first emphasizing the mammalian system as the basis of most terminology and understanding of endocrine mechanisms and then applies that to non-mammals
* Introduces the reader to suitable concepts and explanation of jargon so that the reader will be able to delve directly into the primary literature on any endocrine-related topic with a background that will aid in their interpretation of new information
* Revised and updated chapter on The Molecular Bases for Chemical Regulation that now includes more evolutionary data
* Includes information on endocrine disrupting chemicals and their implications on the health of wildlife and humans
* Companion website includes additional teaching materials such as power point slides of all illustrations in the book.

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• Paperback: 400 pages
• Publisher: McGraw-Hill Professional; 1st edition (March 16, 2006)
• Language: English
• ISBN-10: 0071457445
• ISBN-13: 978-0071457446

Product Description

Featuring the contents of the Endocrinology section of Harrison’s Principles of Internal Medicine, 16th Edition — enhanced with important updates, new and annotated references, new illustrations, and self-assessment/exam review Questions and Answers — this next-generation resource is perfect for the backpack, the wards, and in all clinical situations. Also great for students!

The book offers ease of use, the expertise of renowned editors and contributors, Harrison’s famed coverage of disease mechanisms, invaluable guidelines for ensuring diagnostic accuracy, and state-of-the-art treatment strategies.

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Product Details

• Hardcover: 1904 pages
• Publisher: Saunders; 12 edition (May 31, 2011)
• Language: English
• ISBN-10: 1437703240
• ISBN-13: 978-1437703245

Product Description

The latest edition of Williams Textbook of Endocrinology edited by Drs. Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, and Henry M. Kronenberg, helps you diagnose and treat your patients effectively with up-to-the minute, practical know-how on all endocrine system disorders. Comprehensive yet accessible, this extensively revised 12th Edition updates you on diabetes, metabolic syndrome, obesity, thyroid disease, testicular disorders, and much more so you can provide your patients with the most successful treatments. Find scientific insight and clinical data interwoven in every chapter, reflecting advances in both areas of this constantly changing discipline, and presented in a truly accessible format. You’ll also access valuable contributions from a dynamic list of expert authors and nearly 2.000 full-color images to help you with every diagnosis. Along with convenient online access at www.expertconsult.com, this title has everything you need to manage any and all the clinical endocrinopathies you may encounter.

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Product Details

• Paperback: 360 pages
• Publisher: Wiley; 2 edition (May 25, 2010)
• Language: English
• ISBN-10: 047074216X
• ISBN-13: 978-0470742167

Product Description

Human Drug Metabolism, An Introduction, Second Edition provides an accessible introduction to the subject and will be particularly invaluable to those who already have some understanding of the life sciences. Completely revised and updated throughout, the new edition focuses only on essential chemical detail and includes patient case histories to illustrate the clinical consequences of changes in drug metabolism and its impact on patient welfare.

After underlining the relationship between efficacy, toxicity and drug concentration, the book then considers how metabolizing systems operate and how they impact upon drug concentration, both under drug pressure and during inhibition. Factors affecting drug metabolism, such as genetic polymorphisms, age and diet are discussed and how metabolism can lead to toxicity is explained. The book concludes with the role of drug metabolism in the commercial development of therapeutic agents as well as the pharmacology of some illicit drugs.

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• Paperback: 406 pages
• Publisher: Springer; 1st Edition. edition (March 7, 2011)
• Language: English
• ISBN-10: 1441934502
• ISBN-13: 978-1441934505

Product Description

This book demonstrates how metabolism and energetics are directly linked to those signal transduction pathways that are essential to survival of the cell, the organism, and the species. Recurring patterns of interaction among metabolism, energetics, and signal transduction are fundamental in diverse aspects of human health and disease. This book explores these phenomena in relation to cell growth and death, cancer, atherosclerosis and Alzheimer disease. Part I of the book explores the origins and theory of integration.

Topics covered in Part II include: nutrient and energy metabolism in cell proliferation; fatty acids and growth regulation; mitochondrial function in cell growth and death; metabolic effects of antiproliferative agents; fatty acids and mitochondria, cell growth and injury; metabolism and gene expression.

Part III of the book deals with energetics of neuronal activation; utilization of oxidizable substrates in the brain; astrocyte metabolism and astrocyte-neuron interaction; neuronal energy metabolism in the brain; astroctyes as metabolic buffer and mediator of neuronal injury; and metabolic factors in the pathogenesis of Alzheimer Disease.

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• Paperback: 440 pages
• Publisher: CRC Press; 4 edition (July 17, 2007)
• Language: English
• ISBN-10: 1420043129
• ISBN-13: 978-1420043129

Product Description

Extensively revised and updated to reflect our current understanding of nutritional and dietary requirements, Introduction to Nutrition and Metabolism, Fourth Edition includes new information examining the role of nutrition in common chronic diseases. Also new to this edition are revised end-of-chapter exercises, key point summaries, and a CD-ROM with PowerPoint presentations for each chapter, self-assessment tests, clinical problems, a virtual laboratory, and a program for nutrient analysis and meal evaluation.

Retaining the wealth of detailed information delivered in the accessible manner of its predecessors, this fourth edition continues to provide a clear introduction to the principles of nutrition and metabolism, the interactions between diet and health, and the scientific basis for dietary goals and recommendations. The author uses concise, authoritative language to emphasize and describe the underlying biochemistry that is essential to an understanding of nutrient function and the ability to evaluate and interpret future advances in nutrition science. With clear and simple diagrams, the text explores the physiological need for food and describes the metabolic pathways, their integration and control, and the biochemical basis of their nutritional and physiological importance. It covers digestion and absorption and the metabolic roles of ATP, enzymes, and coenzymes. Describing the functional utilization of protein, fats, and carbohydrates, the book discusses macronutrients in terms of energy yield, energy balance, and reserves. It also covers the endocrinology of metabolic control and the biochemistry of vitamins and minerals.

Examining nutritional biochemistry and the role of diet in heath and disease, Introduction to Nutrition and Metabolism, Fourth Edition provides the scientific basis from which to make prudent and healthy dietary recommendations.

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Product Details

• Hardcover: 312 pages
• Publisher: Human Kinetics; 2 edition (December 16, 2005)
• Language: English
• ISBN-10: 0736041036
• ISBN-13: 978-0736041034

Product Description

Exercise Metabolism, Second Edition, provides a systematic, in-depth examination of the regulation of metabolic processes during exercise. Exercise physiologists, exercise biochemists, and biochemists will find this book a comprehensive reference, using the up-to-date information and the nearly 1,000 references in their own research and writing. In addition, graduate students in these disciplines can learn firsthand about the various regulations of metabolic processes during exercise as they prepare for careers in exercise physiology or biochemistry.

Written by internationally recognized researchers, Exercise Metabolism, Second Edition, is both revised and expanded while retaining the essential elements of the first edition. It delves into the mobilization and utilization of substrates—glucose, lipid, and protein—during physical activity, and it explores metabolic factors in fatigue and metabolic adaptations to endurance training.

Chapter 1 provides an overview of exercise metabolism. Metabolism during high-intensity exercise and the transition from rest to exercise are covered in chapter 2, which details the so-called anaerobic energy pathways. Chapter 3 discusses the effects of exercise on carbohydrate metabolism in skeletal muscle, while chapter 4 provides an overview of the important metabolic functions of the liver during exercise.

Chapter 5 is a new chapter that addresses lactate transport in skeletal muscle, given the increased understanding of this topic since the first edition was published. Chapters 6 and 7 summarize the effects of exercise on lipolysis in adipose tissue and lipid metabolism in skeletal muscle, respectively. The contribution of protein and amino acids to exercise metabolism is discussed in chapter 8. Finally, metabolic factors in fatigue and the metabolic adaptations to endurance training are reviewed in chapters 9 and 10, respectively. Chapter-ending summaries help to condense the information and facilitate understanding.

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Product Details

• Paperback: 440 pages
• Publisher: Wiley; 1 edition (March 30, 2009)
• Language: English
• ISBN-10: 0470122374
• ISBN-13: 978-0470122372

Product Description

Metabolism includes various pathways of chemical reactions; understanding these pathways leads to an improved knowledge of the causes, preventions, and cures for human diseases. Medical Biochemistry: Human Metabolism in Health and Disease provides a concise yet thorough explanation of human metabolism and its role in health and diseases. Focusing on the physiological context of human metabolism without extensive consideration of the mechanistic principles of underlying enzymology, the books serves as both a primary text and resource for students and professional in medical, dental, and allied health programs.

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• Hardcover: 360 pages
• Publisher: Springer; 1 edition (October 31, 1998)
• Language: English
• ISBN-10: 079238217X
• ISBN-13: 978-0792382171

Product Description

Endocrinology of Cardiovascular Function is a fitting inauguration to the Endocrine Update Series. The aim of these publications is to provide the clinician with cutting edge, yet succinct, access to the latest advances in endocrinology. Historically, our understanding of hormonal disturbances was restricted to the classical secretory glands and their targets. As Endocrinology of Cardiovascular Function so aptly indicates, endocrinology is no longer constrained by our early physiologic understanding of glandular disorder. Endocrinology of Cardiovascular Function has set the standard of excellence for the future volumes in this series. Shlomo Melmed, M.D. Series Editor, Endocrine Update Growth factors such as IGF-1 play important roles in cardiovascular cell hypertrophy and the response to acute vascular injury. From another perspective, traditional endocrine hormones, such as estrogen, have been found to participate in preventing the development of atherosclerosis in women, acting through novel mechanisms on target vascular cells. Other `endocrine’ hormones, such as PTHRP and adrenomedullin, also modulate cardiovascular and renovascular dynamic states, suggesting new roles for these peptides as vasodilators. This multi-authored text is dedicated to highlighting emerging and important new information regarding the endocrinology of the cardiovascular system. Ellis R. Levin, M.D.

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Product Details

• Hardcover: 580 pages
• Publisher: Informa Healthcare; 1 edition (September 2002)
• Language: English
• ISBN-10: 1841841862
• ISBN-13: 978-1841841861

Product Description

For a discipline spanning a wide spectrum of conditions and disorders, this is a textbook which provides up-to-date solutions and support. The practising endocrine clinician will find cutting-edge information in a practical format, and help with routine management issues as well as with problems which arise less frequently. Whilst the emphasis is firmly on assessment, investigation, and treatment, the authors have included basic science background for comprehension and completeness, and have expanded this in areas where current research is likely to impinge upon clinical practice.

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Product Details

• Hardcover: 316 pages
• Publisher: Springer; 1st Edition. edition (April 22, 2010)
• Language: English
• ISBN-10: 1441955755
• ISBN-13: 978-1441955753

Product Description

Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. This book will introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can directly respond to neuroendocrine hormones, as evidenced by increased growth and production of virulence-associated factors, provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that the neuroendocrine hormones that one most commonly associates with mammals are actually found throughout the plant, insect and microbial communities to an extent that will undoubtedly surprise many, and most importantly, how interactions between microbes and neuroendocrine hormones can influence the pathophysiology of infectious disease.

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